therapeutics

Therapeutics

Identification and validation of novel treatment targets and the design of innovative treatment strategies using diverse approaches, including in silico models, preclinical studies, and human model systems, to enhance our understanding of brain diseases and develop effective therapies.

New Target Identification

Identification of novel druggable targets through advanced techniques such as single-cell sequencing, spatial transcriptomics, and systems neuroscience.

Target Validation

Validation of the therapeutic potential of new drugs through a wide range of experimental models, including in vitro approaches, preclinical studies, and human model systems.

Drug Delivery Systems

Design of translatable drug delivery systems to optimise the treatment of brain conditions through innovative techniques such as gene therapy, adeno-associated virus (AAV) vectors, antisense oligonucleotides, optogenetics, chemogenetics, and CRISPR technology.