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Blood-brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment

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Background

Long COVID has remained an on-going public health issue in the years following the global pandemic. Here, we report that the network of small blood vessels in the human brain is disrupted in patients with long COVID and brain fog.

Research

Our aim was to examine the integrity of the blood vessels in the brain in patients suffering from neurological disorder and long COVID.

Potential Impact

By pinpointing damage to the blood vessels in the brain, we may now be able to develop targeted therapies for individuals experiencing the long-term effects of COVID-19. It is our vision that targeted regulation of the blood brain barrier (BBB) will change the landscape of how neurological disorders are treated in the future.

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