Background

The genetic history of Ireland and Britain has been shaped by migration, settlement patterns, and population size differences over time. Understanding these historical influences helps researchers interpret genetic variations in modern populations and their implications for health and disease.

Research

The genetic history of Ireland and Britain was analysed by recording regions of the genome shared by individuals with ancestry from specific Irish and British regions. This approach revealed how the genetic landscape has evolved over time. For the first time, Irish genetic data was also linked to genealogical records, revealing distinct surname patterns tied to genetic communities, influenced by Scottish, English, Viking, and Anglo-Norman settlements.

Impact

This research enhances our understanding of Ireland’s genetic heritage and migration patterns. By mapping historical population movements and surname distributions, it provides valuable insights for genetic studies on rare diseases, particularly those affecting Irish and Irish-ancestry communities. A deeper knowledge of Ireland’s genetic diversity will help scientists identify disease-related genetic factors more effectively, paving the way for improved diagnostics and potential new treatments.